Apolipoprotein e4 allele and cognitive decline
نویسندگان
چکیده
منابع مشابه
Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease.
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متن کاملThe Apolipoprotein E e4 Allele and Outcome in Cerebrovascular Disease
Background and Purpose—Polymorphism of the apolipoprotein E gene (APOE) may influence outcome after traumatic brain injury and intracerebral hemorrhage, with the e4 allele being associated with poorer prognosis. We investigated APOE allele distribution in acute stroke and the effect of the e4 allele on outcome. Methods—APOE genotypes were determined in 714 stroke patients: 640 ischemic stroke a...
متن کاملStroke and Apolipoprotein E e4 Are Independent Risk Factors for Cognitive Decline A Population-Based Study
Decline : A Population-Based Study Stroke and Apolipoprotein E e4 Are Independent Risk Factors for Cognitive ISSN: 1524-4628 Copyright © 2000 American Heart Association. All rights reserved. Print ISSN: 0039-2499. Online Stroke is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX 72514 2000, 31:2431-2436 Stroke http://stroke.ahajournals.org/content/31/10/2431 locat...
متن کاملAmyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people.
BACKGROUND The neurobiological changes underlying the association of the apolipoprotein E (APOE) e4 allele with level of cognition are poorly understood. OBJECTIVE To test the hypothesis that amyloid load can account for (mediate) the association of the APOE e4 allele with level of cognition assessed proximate to death. METHODS There were 44 subjects with clinically diagnosed Alzheimer's di...
متن کاملHerpes Simplex-1 As An Additive Risk Factor for Cognitive Decline in Apolipoprotein E4 Carriers Committee:
.............................................................................................................................25 3.0 Introduction..................................................................................................................26 3.1 Methods .......................................................................................................................28 3....
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ژورنال
عنوان ژورنال: BMJ
سال: 1995
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.310.6975.330a